What are hormone pellets?

Bio-identical hormone pellets are obtained in various strengths of estradiol and testosterone from a highly rated commercially licensed compounding pharmacy. The hormones are derived from an ingredient found in many vegetables including yams and soy beans. The hormones are pressed or fused into very small solid cylinders that are smaller than a grain of rice and smaller than a ‘tic tac.’

Why pellets?

Pellets deliver consistent levels of hormones for 4-6 months. They avoid the fluctuations of hormone levels seen with other methods of delivery. In studies, compared to conventional hormone replacement therapy, pellets have been shown to be superior for relief of menopausal symptoms, maintenance of bone density, restoration of sleep patterns, and improvement in sex drive, libido, sexual response.

Many patients who fail other types of hormone therapy find a high success with hormone pellets. There is no other method of hormone delivery that is as convenient for the patient as pellets. Pellets have been used in both men and women since the late 1930’s.

How are pellets inserted?

The insertion of pellets is a simple, relatively painless procedure done under local anesthesia. The pellets are usually inserted in the upper buttocks in a small incision, which is then covered with a small bandage or steri-strips. The experience of the health care professional matters a great deal, not only in the placement of pellets, but also in determining the correct dosage of hormones to be used.

Interested in learning more about hormone pellets? Reach out to us at Avant Gynecology for an appointment.


Avant Gynecology serves patients at two locations: Piedmont Hospital in Buckhead and Northside Hospital. Our mission at Avant Gynecology is to provide exceptional, compassionate care to women at every stage of their lives. Our providers strive to be at the forefront of knowledge and skill in the fields of women’s health and gynecologic surgery, so our patients can get the best care possible. Avant provides state-of-the-art surgery services and comprehensive gynecologic care, such as annual exams, diagnostic and screening tests; a full range of contraceptive options; specialized services such as bio-identical hormone therapy, hormone pellets, ThermiVa vaginal rejuvenation, and more.