What Is Pro-Nox™?

Pro-Nox™ is a patient-controlled analgesia system that delivers a 50/50 mixture of nitrous oxide (commonly known as “laughing gas”) and oxygen. This combination provides quick relief from pain and anxiety, allowing patients to remain conscious and responsive during their procedure.

Uses of Pro-Nox™

Pro-Nox™ can be used for pain and anxiety relief during various procedures, including:

  • Intrauterine Device (IUD) Placement and Removal
  • Endometrial Biopsies
  • Colposcopies
  • Cryotherapy and LEEP Procedures
  • In-office Hysteroscopies
  • Labiaplasty
  • Saline-Infused Sonohysterography
  • Other minor surgical procedures

Why Choose Pro-Nox™?

  • Patient-Controlled: Allows you to manage your comfort levels. You decide when and how much gas to self-administer based on your own comfort needs.
  • Rapid Onset and Offset: Quick relief that wears off rapidly within 1-3 minutes.
  • Safe and Effective: This FDA-approved system has a proven track record in various medical settings.

Expected Experience

The Pro-Nox™ system is designed to be user-friendly and empowering for patients. Here’s what you can expect:

  1. Self-Administration: You control the intake of Pro-Nox™, taking breaths as needed to manage your comfort. The gas is only delivered when you inhale through the mouthpiece.
  2. Immediate Effect: The effects are almost immediate, offering relief of pain and anxiety within seconds of inhalation.
  3. Quick Recovery: Pro-Nox™ clears from your system quickly, allowing you to recover almost immediately after the procedure. You can resume normal activities soon after your procedure, as the effects wear off within minutes.

Side Effects

Pro-Nox™ is generally very well-tolerated, but some patients may experience minor side effects that are short-lived and subside quickly after discontinuation of the gas, such as dizziness and nausea.


While Pro-Nox™ is safe for most patients, there are some contraindications to consider including pregnancy, hypersensitivity to nitrous oxide, vitamin B12 deficiency, certain respiratory conditions like pneumothorax, active ear infection, middle ear occlusion, eye surgery with intra-ocular gas injection within the last 6 weeks, decompression sickness, and severe abdominal distension due to intestinal obstruction.


The cost of adding Pro-Nox™ to your procedure is an additional $100 out-of-pocket expense due at time of the procedure. This fee covers the use of the Pro-Nox™ system, ensuring you have a comfortable and anxiety-free experience.

We believe that every patient deserves a comfortable and stress-free experience during their gynecological procedures. By offering Pro-Nox™, we aim to enhance your overall experience and ensure you receive the best care possible.

If you have any questions about Pro-Nox™ or would like to schedule an appointment, please contact our office today.